Mar
10

NutriCee Syrup

Ascorbic Acid + Zinc Gluconate

NutriCee Plus Zinc

100 mg/35 mg per 5 mL Syrup

Vitamin/Mineral


FORMULATION:

Each 5 mL drops contains:

Ascorbic Acid …… 100 mg

Zinc Gluconate …… 35 mg

(Equivalent to 5 mg Elemental Zinc)

RECOMMENDED DOSE:

2 to 6 years: 5 mL (1 teaspoonful)

7 to 12 years: 10 mL (2 teaspoonfuls)

To be taken once a day for supplementation. 2 to 4 times a day for therapeutic use or as prescribed by the physician.

INDICATIONS:

Ascorbic acid (Vitamin C) a water soluble vitamin, is essential for the synthesis of collagen and intercellular material. Vitamin C deficiency develops when the dietary intake is inadequate. It is rare in adults, but may occur in infants, alcoholics, or the elderly. Deficiency leads to the development of a well-defined syndrome known as scurvy. This is characterized by capillary fragility, bleeding (especially from small blood vessels and the gums), normocytic or macrocytic anaemia, cartilage and bone lesions and slow healing of wounds. Vitamin C is used in the treatment and prevention of deficiency. It completely reverses symptoms of deficiency. Zinc has been proven to help in the proper growth and development of children. Zinc also helps in the correction and prevention of the most common childhood infections like pneumonia and diarrhea.

PHARMACOKINETICS/PHARMACODYNAMICS:

Ascorbic acid is readily absorbed from the gastrointestinal tract and is widely distributed in the body tissues. Plasma concentrations of ascorbic acid rise as the dose ingested is increased until a plateau is reached with doses of about 90 to 150 mg daily. Body stores of ascorbic acid in health are about 1.5 g although more may be stored at intakes above 200 mg daily.

Ascorbic acid is reversibly oxidised to dehydroascorbic acid; some is metabolised to ascorbate-2-sulfate, which is inactive, and oxalic acid which are excreted in the urine. Ascorbic acid crosses the placenta and is distributed into breast milk. It is removed by haemodialysis.

CONTRAINDICATION:

Contraindicated in individuals who have shown hypersensitivity to any component of this preparation.

WARNINGS:

Diabetics, patients prone to recurrent renal calculi, those undergoing stool occult blood tests, and those on sodium-restricted diets or anticoagulant therapy should not take excessive doses of vitamin C over an extended period of time.

PRECAUTIONS:

Ascorbic acid (Vitamin C) is usually well tolerated. Large doses are reported to cause diarrhea, other gastrointestinal disturbances and may result in hyperoxaluria and formation of renal calcium oxalate calculi.

INTERACTIONS WITH OTHER MEDICAMENTS:

Ascorbic acid should not be given during the first month after starting desferrioxamine treatment because there is some evidence that ascorbic acid may worsen the iron
toxicity due to excess tissue iron.

Large supplements of ascorbic acid have been reported to increase serum ethinylestradiol concentrations in women taking oral contraceptives.

Administration of ascorbic acid for vitamin C deficiency to a patient receiving fluphenazine for bipolar disorder was associated with a fall in serum concentrations of fluphenazine and a deterioration of behaviour.

UNDESIRABLE EFFECTS:

Tolerance may be induced with prolonged use of large doses, resulting in symptoms of deficiency when intake is reduced to normal.

Large doses of ascorbic acid have resulted in haemolysis in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency.

AVAILABILITY:

120 mL amber bottle.

STORE AT TEMPERATURES NOT EXCEEDING 30oC.

PROTECT FROM LIGHT.