Mar
06

Esvical Forte

ESVICAL forte

Chewable Tablet


FORMULATION:

Each chewable tablet contains:

Calcium Carbonate ………… 750 mg (equivalent to 300 mg elemental calcium)
Cholecalciferol (Vitamin D3) ………… 10 iu
Simethicone ………… 10 mg

ESVICAL forte chewable tablet is a unique and comprehensive calcium supplement that augments calcium obtained from the diet.

Calcium is one of the major minerals which occurs in very large amounts in the body. It performs the following physiologic functions:

Blood clotting – calcium is important in clotting by helping in the formation of fibrin to form the clot.

Muscle and nerve activities – Calcium ions are essential in muscle contraction and in the transmission of nerve impulses. Calcium is also involved in the normal functioning of the heart.

Bone and teeth formation – About 99% of body calcium is found in the bones. Calcium is an important inorganic constituent required to form and develop the bones. It is essential for bone growth and mineralization. Calcium is therefore responsible in maintaining bone hardness and rigidity.

Metabolic Functions – Calcium is also necessary in maintaining permeability of cell membranes to nutrients, in the absorption of vitamin B12 and in other body enzyme systems.

Calcium deficiency may result in rickets (bone deformity in children related to vitamin D deficiency), tetany (abnormal spasm of muscles of the upper extremities), delay in blood clotting, disturbances in muscle and nerve functions, growth stunting among children, and osteoporosis in the elderly.

Calcium supplementation is specially required among growing children, adolescents, pregnant and lactating women, post-menopausal women, the elderly and those with fracture.

Calcium is one of the minerals most likely to be deficient in the diet. The deficiency appears to result from either economic reasons or from food preferences. Some individuals find it difficult to meet their daily requirement for calcium because they develop an aversion to foods rich in calcium.

Others lack knowledge about the good dietary sources of calcium. Children who have lactose intolerance and who consume limited amounts of milk products are at risk of developing calcium deficiency. As males are more likely to take adequate amounts of calcium because they usually eat larger amounts of food, females are more susceptible to calcium deficiency.

As it may be difficult for an individual to get enough calcium from the diet alone, calcium supplementation like Esvical forte chewable tablet becomes necessary.

Considering that bone growth or major increase in bone mass occurs during adolescence and early adulthood, high calcium intake becomes highly essential during this period. Inadequate calcium intake limits linear bone growth and mineralization.

There is increased calcium requirement during pregnancy and lactation to meet the demands for fetal bone formation. Additional calcium must be stored in the maternal skeleton to provide a reserve source of calcium during lactation.

When there is inadequate calcium intake, calcium is mobilized or withdrawn from the bones to meet the body requirements. The bones are weakened and become thin.

Calcium supplementation is important at any stage of a person’s life since the bones are constantly being remodeled throughout life.

In children and adolescents, there is increased rate of bone formation. As the person grows older, the rate of demineralization or bone resorption exceeds the rate of bone formation. The bone is resorbed or broken down faster than the body can replace it.

Bone mass decreases and the bone becomes thinner and weaker, a medical condition known as osteoporosis.

Osteoporosis is characterized by an abnormal thinning of bone producing a porous, fragile, lattice-like bone tissue with enlarged spaces. This is caused by increased bone resorption compared to a relatively decreased rate of bone formation. As there is decreased bone density, the bones become fragile and prone to fracture or deformity. Individuals with osteoporosis have generalized skeletal fragility. The most common sites of fracture are the spine (vertebral column), hip (proximal femur) and forearm (wrist).

Osteoporosis is recognized worldwide as a major public health problem among the elderly. It develops as a result of bone loss in aging individuals or when there is failure to achieve desired bone mass during childhood and adolescence.

Elderly individuals are more vulnerable to osteoporosis. Women are more vulnerable than men because adult females have less bone mass to begin with than adult males. Also, after menopause, bone loss accelerates in women because of the lack of estrogen.

Older people don’t consume sufficient dairy products as a result of decreased food intake, concomitant illnesses and lactose intolerance. Some older individuals have reduced lactase, a substance that digests the so-called milk sugar or lactose.

The bone is not a “static” organ as most people think. Rather, bone undergoes continuous formation (mineralization) and destruction (demineralization or bone resorption), a process called remodeling.

While in childhood and adolescence, calcium is needed for bone building, in the elderly, calcium is important to delay or prevent further bone depletion.

Bone remodeling is affected by several factors including physical activity, stress or bone injury like fracture. Bone remodeling is extensive during fracture healing so there is a need to provide extra calcium during this stage. As continuous bone remodeling occurs throughout life, there must be continuous and adequate daily supplement of calcium.

Esvical forte chewable tablet provides a comprehensive approach against osteoporosis and other calcium deficiency states because it contains 750 mg calcium carbonate equivalent to 300 mg elemental calcium, 10 iu of vitamin D and 10 mg of simethicone. Vitamin D promotes calcium absorption by enhancing the formation of calcium-binding protein that facilitates the transport of calcium. Simethicone with its antifoaming properties, prevents mild gastrointestinal discomfort associated with the intake of calcium.

DOSAGE:

Calcium Supplement:
Chew 2 tablets twice daily. Average daily consumption should not exceed 8 tablets.
Antacid:
Chew 2 – 4 tablets as symptoms occur (or as prescribed by the physician).

INDICATION:

As a daily source of extra calcium or for the relief of hyperacidity.

DRUG INTERACTION / PRECAUTION:

Antacids may interact with certain prescription drugs. If you are presently taking a prescription drug, do not take this product without checking with your physician or other health professionals.

Safety of simethicone for long term use in pregnancy is not yet established as there are no available controlled studies in women and animals.

WARNING:

It can cause constipation. Hypercalcemia and alkalosis may occur with large doses. Do not take more than 10 tablets in a 24-hour period or use the maximum dosage of this product for more than two weeks, except under the advice and supervision of a physician.