Mar
06

Mucovis Syrup

AMBROXOL HCI

MUCOVIS

Syrup

MUCOLYTIC


FORMULATION:

Each 5 mL (one teaspoonful) contains:

Ambroxol HCI ………… 15 mg

PROPERTIES:

AMBROXOL HCI, as a mucolytic, facilitates the expectoration of abnormal secretions present in the upper and lower respiratory tract.

AMBROXOL HCI breaks and liquefies the acid mucopolysaccharide fibers of the mucus, making it thinner and less viscid. The sputum becomes less tenacious and less sticky, thus allowing easier expectoration.

AMBROXOL stimulates mucociliary activity and enhances production of naturally occurring surfactants. It alters the structure of mucus to reduce its viscosity. Enhancement of mucociliary function and fluid secretion facilitates expectoration of mucus present in the upper and lower respiratory tract.

PHARMACOKINETICS:

Ambroxol is rapidly and completely absorbed in the gastrointestinal tract and concentrates in the lungs. Maximum plasma level is reached within one half to three hours. Its plasma half-life is eight to twelve hours. Ambroxol HCl is metabolized mainly in the liver and eliminated thru the urine.

INDICATIONS:

Ambroxol is used in the treatment of acute and chronic respiratory tract disorders associated with abnormal bronchial mucus secretions such as bronchitis, bronchial asthma, pneumonia and other pulmonary diseases. It is also used as an adjuvant in the treatment of sinusitis, rhinitis and other inflammatory diseases of the nasal cavity and throat when treatment of such conditions require a mucolytic.

DOSAGE:

Adults and children over 12 years: 10 mL (2 tsps.) 3 times daily

Children under 12 years:
6 – 12 years: 5 mL (1 tsp.) 2-3 times daily
2 – 6 years: 2.5 mL (1/2 tsp.) 3 times daily
1 – 2 years: 2.5 mL (1/2 tsp.) 2 times daily

Or as prescribed by the physician.

CONTRAINDICATIONS/PRECAUTIONS:

Ambroxol should not be used in patients with history of hypersensitivity to ambroxol and bromhexine.

Ambroxol should be given cautiously to patients with history of gastric ulceration.

ADVERSE REACTIONS:

Ambroxol is generally well tolerated. Occasional or mild gastrointestinal irritation and discomfort such as diarrhea, abdominal fullness and nausea may occur.

CAUTION:

Foods, Drugs, Devices and Cosmetics Act prohibits dispensing without prescription.

AVAILABILITY:

15 mg/5 mL in 60 mL amber bottles

STORE AT TEMPERATURES NOT EXCEEDING 30ºC.

PROTECT FROM LIGHT.